La aterosclerosis se manifiesta frecuentemente en la quinta o sexta década de la vida en los hombres y unos 10 años más tarde en las mujeres.

SHAPE-Certified Clinic

Traditionally, screening for prevention of heart attack and stroke has relied on assessment of cardiovascular risk factors. This approach, set forth by the National Cholesterol Education Program (NCEP), identifies high risk individuals solely based on age, blood pressure, cholesterol, smoking, and diabetes. 

In 2006, the SHAPE Task Force authored the SHAPE Guidelines for screening asymptomatic population, which includes specific recommendations for non-invasive detection and treatment of subclinical atherosclerosis in middle-aged, at-risk population.